Inflammasome activation and reduced sTREM2 release in LPS stimulated organotypic brain slices
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چکیده
منابع مشابه
LPS pretreatment reprograms macrophage LPS-stimulated TNF and IL-1 release without protein tyrosine kinase activation.
Pretreatment of macrophages with low-dose endotoxin (LPSp) profoundly alters cytokine release in response to subsequent LPSa activation. These qualitative and quantitative alterations in cytokine release have been termed macrophage reprogramming. Macrophage activation by LPS is thought to occur via a mechanism involving an early protein tyrosine kinase (PTK) phosphorylation step. PTK inhibition...
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ژورنال
عنوان ژورنال: Alzheimer's & Dementia
سال: 2020
ISSN: 1552-5260,1552-5279
DOI: 10.1002/alz.042691